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Science 3 November 1995:
Vol. 270. no. 5237, pp. 732 - 733
DOI: 10.1126/science.270.5237.732
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Research News

Marcia Barinaga

Organisms from simple, single-celled bacteria to complex mammals have internal biochemical clocks that maintain the daily cycles of behavior known as circadian rhythms. In three reports published in this issue of Science (pp. 805, 808, and 811), researchers have cloned a gene called timeless that makes a key protein component of the clock in the fruit fly Drosophila melanogaster. By studying how TIM, the protein made by timeless, cooperates with PER, the protein produced by the only other known fruit fly clock gene, researchers are getting a much clearer picture of the molecular workings of the fly's circadian clock.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
A PER/TIM/DBT Interval Timer for Drosophila's Circadian Clock.
L. Saez, P. Meyer, and M. W. Young (2007)
Cold Spring Harb Symp Quant Biol 72, 69-74
   Abstract »    PDF »
Is Perception of Light Useful to the Blind Patient?.
R. D. Ross (1998)
Arch Ophthalmol 116, 236-238
   Full Text »    PDF »


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