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Science 5 December 2008:
Vol. 322. no. 5907, pp. 1567 - 1570
DOI: 10.1126/science.322.5907.1567
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From the AAAS Office of Publishing and Member Services

BUSINESS OFFICE FEATURE:
Life Science Technologies: Cell Signaling: ChIPping Away at Gene Expression

Mike May

Chromatin immunoprecipitation reveals where proteins interact with DNA, and advances in this technology—including simplified applications, improved sensitivity, and higher throughput—allow scientists to track increasingly complex details of gene regulation in normal development and disease conditions.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)