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Science 14 November 2008:
Vol. 322. no. 5904, pp. 1062 - 1063
DOI: 10.1126/science.1166485
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Perspectives

MICROBIOLOGY:
A Protein Pupylation Paradigm

Sohini Mukherjee1 and Kim Orth2

Tagging proteins with ubiquitin molecules so that they will be degraded in the proteasome is not a mechanism unique to eukaryotes.

1Department of Immunology, University of Texas Southwestern Medical School, Dallas, TX 75230, USA.

2Department of Molecular Biology, University of Texas Southwestern Medical School, Dallas, TX 75230, USA. E-mail: kim.orth{at}utsouthwestern.edu

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Science. ISSN 0036-8075 (print), 1095-9203 (online)