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Science 5 September 2008:
Vol. 321. no. 5894, pp. 1302 - 1304
DOI: 10.1126/science.1163791
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Perspectives

MEDICINE:
The Cart Before the Horse

Janet D. Rowley1 and Thomas Blumenthal2

Chimeric RNAs, transcribed from malignancy-associated chromosomal translocations, can also arise from RNA trans-splicing in normal cells.

1Department of Medicine, University of Chicago, 5841 South Maryland Avenue, MC 2115, Chicago, IL 60637, USA. E-mail: jrowley{at}medicine.bsd.uchicago.edu

2Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309, USA. E-mail: tom.blumenthal{at}colorado.edu

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Mutation-associated fusion cancer genes in solid tumors.
F. J. Kaye (2009)
Mol. Cancer Ther. 8, 1399-1408
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Science. ISSN 0036-8075 (print), 1095-9203 (online)