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Science 6 June 2008:
Vol. 320. no. 5881, pp. 1361 - 1365
DOI: 10.1126/science.320.5881.1361

From the AAAS Office of Publishing and Member Services

BUSINESS OFFICE FEATURE:
Life Science Technologies: Hotter Than Hot—Combining RNAi and Stem Cells

Alan Dove

Ten years ago, RNA interference was an interesting but arcane phenomenon that excited a small group of researchers working on Caenorhabditis elegans. At the same time, embryonic stem cells were a useful but cumbersome system for engineering targeted gene deletions in mice. Neither tool seemed to have much use beyond its narrowly defined specialty. What a difference a decade makes.





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Science. ISSN 0036-8075 (print), 1095-9203 (online)