Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.


Science 25 April 2008:
Vol. 320. no. 5875, pp. 461 - 462
DOI: 10.1126/science.1158680

Perspectives

CELL BIOLOGY:
RNA Metabolism and Oncogenesis

Deborah L. Johnson and Sandra A. S. Johnson*

Regulating the production of RNAs involved in protein synthesis can induce the transformation of cells to an oncogenic state.


Department of Biochemistry and Molecular Biology, University of Southern California, Los Angeles, CA 90033, USA. E-mail: johnsond{at}hsc.usc.edu

Read the Full Text


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
TLS Inhibits RNA Polymerase III Transcription.
A. Y. Tan and J. L. Manley (2010)
Mol. Cell. Biol. 30, 186-196
   Abstract »    Full Text »    PDF »
Dr1 (NC2) is present at tRNA genes and represses their transcription in human cells.
T. Kantidakis and R. J. White (2009)
Nucleic Acids Res.
   Abstract »    Full Text »    PDF »
The JNKs differentially regulate RNA polymerase III transcription by coordinately modulating the expression of all TFIIIB subunits.
S. Zhong and and D. L. Johnson (2009)
PNAS 106, 12682-12687
   Abstract »    Full Text »    PDF »



To Advertise     Find Products


Science. ISSN 0036-8075 (print), 1095-9203 (online)