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Science 9 November 2007:
Vol. 318. no. 5852, p. 914
DOI: 10.1126/science.1143320
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Technical Comments

Response to Comment on "A G Protein–Coupled Receptor Is a Plasma Membrane Receptor for the Plant Hormone Abscisic Acid"

Xigang Liu,1 Yanling Yue,1 Wei Li,1,2 Ligeng Ma1*

Our study provided experimental evidence that GCR2 is a membrane-associated abscisic acid receptor that interacts with the G protein {alpha} subunit GPA1 in Arabidopsis. Although we cannot rule out GCR2 as a lanthionine synthetase homolog, our data indicate that it may define a new type of nonclassical G protein–coupled receptor.

1 National Institute of Biological Sciences, 7 Science Park Road, Zhongguancun Life Science Park, Beijing 102206, China.
2 Laboratory of Molecular Cellular Biology, Hebei Normal University, Shijiazhuang, Hebei 050016, China.

* To whom correspondence should be addressed. E-mail: maligeng{at}nibs.ac.cn

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Abscisic Acid Receptors: Multiple Signal-perception Sites.
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E-Letters:

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What Is the Distinct Function of GCR2?
Huaiyu Sun
Science Online, 10 Dec 2007 [Full text]

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