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Science 9 November 2007:
Vol. 318. no. 5852, p. 913
DOI: 10.1126/science.318.5852.913a
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John P. Moore; Rickye S. Heffner; Stephen W. Director
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Technical Comment Abstracts


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Technical Comment Abstracts

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COMMENT ON "A G Protein-Coupled Receptor Is a Plasma Membrane Receptor for the Plant Hormone Abscisic Acid"
Christopher A. Johnston, Brenda R. Temple, Jin-Gui Chen, Yajun Gao, Etsuko N. Moriyama, Alan M. Jones, David P. Siderovski, Francis S. Willard
Abstract: Liu et al. (Reports, 23 March 2007, p. 1712) reported that the Arabidopsis thaliana gene GCR2 encodes a seven-transmembrane, G protein-coupled receptor for abscisic acid. We argue that GCR2 is not likely to be a transmembrane protein nor a G protein-coupled receptor. Instead, GCR2 is most likely a plant homolog of bacterial lanthionine synthetases.

Full text at www.sciencemag.org/cgi/content/full/318/5852/914c

 

RESPONSE TO COMMENT ON "A G Protein-Coupled Receptor Is a Plasma Membrane Receptor for the Plant Hormone Abscisic Acid"
Xigang Liu, Yanling Yue, Wei Li, Ligeng Ma
Abstract: Our study provided experimental evidence that GCR2 is a membrane-associated abscisic acid receptor that interacts with the G protein alpha subunit GPA1 in Arabidopsis. Although we cannot rule out GCR2 as a lanthionine synthetase homolog, our data indicate that it may define a new type of nonclassical G protein-coupled receptor.

Full text at www.sciencemag.org/cgi/content/full/318/5852/914d

 

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