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Science 27 April 2007:
Vol. 316. no. 5824, p. 530
DOI: 10.1126/science.316.5824.530
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News of the Week

GENETICS:
Erasing MicroRNAs Reveals Their Powerful Punch

Jennifer Couzin

In a flurry of papers, three of which appear on pages 575, 604, and 608 of this issue of Science, four independent groups have for the first time deleted mouse genes for microRNAs, RNA molecules that can modulate gene behavior, with profound effects. (Read more.)

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
miRo: a miRNA knowledge base.
A. Lagana, S. Forte, A. Giudice, M. R. Arena, P. L. Puglisi, R. Giugno, A. Pulvirenti, D. Shasha, and A. Ferro (2009)
Database 2009, bap008
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Estradiol downregulates miR-21 expression and increases miR-21 target gene expression in MCF-7 breast cancer cells.
N. S. Wickramasinghe, T. T. Manavalan, S. M. Dougherty, K. A. Riggs, Y. Li, and C. M. Klinge (2009)
Nucleic Acids Res. 37, 2584-2595
   Abstract »    Full Text »    PDF »


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