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Science 30 March 2007:
Vol. 315. no. 5820, pp. 1800 - 1801
DOI: 10.1126/science.1141279
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Perspectives

MEDICINE:
Anticipating Trouble from Gene Transcription

Mark E. Fortini

By forcing the fruit fly to transcribe repeat regions, a model of certain human neurological disorders has been developed, which suggests new possibilities for understanding repeat instability.

The author is in the Cancer and Developmental Biology Laboratory, National Cancer Institute, Frederick, MD 21702, USA. E-mail: fortini{at}ncifcrf.gov

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Naturally Extended CT {middle dot} AG Repeats Increase H-DNA Structures and Promoter Activity in the Smooth Muscle Myosin Light Chain Kinase Gene.
Y.-J. Han and P. de Lanerolle (2008)
Mol. Cell. Biol. 28, 863-872
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Science. ISSN 0036-8075 (print), 1095-9203 (online)