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Science 23 March 2007:
Vol. 315. no. 5819, p. 1633
DOI: 10.1126/science.315.5819.1633n
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For trichromatic color vision, an animal needs three distinct visual pigments expressed separately in individual photoreceptors, and the animal must also be able to process the information in the retina and visual cortex. Mice do not have trichromatic vision, because they only possess two visual pigments. Jacobs et al. (p. 1723) examined the spectral and behavioral properties of mice genetically engineered to express a third visual pigment. The human long-wavelength opsin was knocked-in to form an X-linked polymorphism. When the engineered mice expressed pigments in the correct ratios, they exhibited behavior consistent with functional trichromatic vision.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)