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Science 16 March 2007:
Vol. 315. no. 5818, pp. 1507 - 1508
DOI: 10.1126/science.1140736
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Perspectives

STRUCTURAL BIOLOGY:
A Glimpse of Biology's First Enzyme

Gerald F. Joyce

The structure of an RNA enzyme that catalyzes the joining of RNA has been solved, providing insight into what may have been the most ancient enzyme of biology.

The author is in the Departments of Chemistry and of Molecular Biology, The Scripps Research Institute, La Jolla, CA 92037, USA. E-mail: gjoyce{at}scripps.edu

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
An RNA-making reactor for the origin of life.
E. V. Koonin (2007)
PNAS 104, 9105-9106
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Science. ISSN 0036-8075 (print), 1095-9203 (online)