Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.


Originally published in Science Express on 21 December 2006
Science 26 January 2007:
Vol. 315. no. 5811, pp. 466 - 467
DOI: 10.1126/science.1138239

Perspectives

GENETICS:
SNPs, Silent But Not Invisible

Anton A. Komar

Single nucleotide polymorphisms that are considered "silent" can affect protein folding.


The author is in the Department of Biological, Geological and Environmental Sciences, Cleveland State University, Cleveland, OH 44115, USA. E-mail: a.komar{at}csuohio.edu

Read the Full Text



THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Vitamin D Related Genes, CYP24A1 and CYP27B1, and Colon Cancer Risk.
L. M. Dong, C. M. Ulrich, L. Hsu, D. J. Duggan, D. S. Benitez, E. White, M. L. Slattery, F. M. Farin, K. W. Makar, C. S. Carlson, et al. (2009)
Cancer Epidemiol. Biomarkers Prev. 18, 2540-2548
   Abstract »    Full Text »    PDF »
Translationally Optimal Codons Associate with Structurally Sensitive Sites in Proteins.
T. Zhou, M. Weems, and C. O. Wilke (2009)
Mol. Biol. Evol. 26, 1571-1580
   Abstract »    Full Text »    PDF »
Investigating Protein-Coding Sequence Evolution with Probabilistic Codon Substitution Models.
M. Anisimova and C. Kosiol (2009)
Mol. Biol. Evol. 26, 255-271
   Abstract »    Full Text »    PDF »
Where Do We Go for Atherothrombotic Disease Genetics?.
S.-M. Brand-Herrmann (2008)
Stroke 39, 1070-1075
   Full Text »    PDF »
GATA4 sequence variants in patients with congenital heart disease.
A Tomita-Mitchell, C L Maslen, C D Morris, V Garg, and E Goldmuntz (2007)
J. Med. Genet. 44, 779-783
   Abstract »    Full Text »    PDF »
Raising the estimate of functional human sequences.
M. Pheasant and J. S. Mattick (2007)
Genome Res. 17, 1245-1253
   Abstract »    Full Text »    PDF »
Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome.
E. H. Margulies, G. M. Cooper, G. Asimenos, D. J. Thomas, C. N. Dewey, A. Siepel, E. Birney, D. Keefe, A. S. Schwartz, M. Hou, et al. (2007)
Genome Res. 17, 760-774
   Abstract »    Full Text »    PDF »
Frequency and phenotypic implications of mitochondrial DNA mutations in human squamous cell cancers of the head and neck.
S. Zhou, S. Kachhap, W. Sun, G. Wu, A. Chuang, L. Poeta, L. Grumbine, S. K. Mithani, A. Chatterjee, W. Koch, et al. (2007)
PNAS 104, 7540-7545
   Abstract »    Full Text »    PDF »



To Advertise     Find Products


Science. ISSN 0036-8075 (print), 1095-9203 (online)