Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.
Single nucleotide polymorphisms that are considered "silent" can affect protein folding.
The author is in the Department of Biological, Geological and Environmental Sciences, Cleveland State University, Cleveland, OH 44115, USA. E-mail: a.komar{at}csuohio.edu
The editors suggest the following Related Resources on Science sites:
In Science Magazine
REPORTS
Chava Kimchi-Sarfaty, Jung Mi Oh, In-Wha Kim, Zuben E. Sauna, Anna Maria Calcagno, Suresh V. Ambudkar, and Michael M. Gottesman (26 January 2007) Science315 (5811), 525.
[DOI: 10.1126/science.1135308] |Abstract »|Full Text »|PDF »|Supporting Online Material »
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Vitamin D Related Genes, CYP24A1 and CYP27B1, and Colon Cancer Risk.
L. M. Dong, C. M. Ulrich, L. Hsu, D. J. Duggan, D. S. Benitez, E. White, M. L. Slattery, F. M. Farin, K. W. Makar, C. S. Carlson, et al. (2009)
Cancer Epidemiol. Biomarkers Prev.
18, 2540-2548
|Abstract »|Full Text »|PDF »
Translationally Optimal Codons Associate with Structurally Sensitive Sites in Proteins.
Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome.
E. H. Margulies, G. M. Cooper, G. Asimenos, D. J. Thomas, C. N. Dewey, A. Siepel, E. Birney, D. Keefe, A. S. Schwartz, M. Hou, et al. (2007)
Genome Res.
17, 760-774
|Abstract »|Full Text »|PDF »
Frequency and phenotypic implications of mitochondrial DNA mutations in human squamous cell cancers of the head and neck.
S. Zhou, S. Kachhap, W. Sun, G. Wu, A. Chuang, L. Poeta, L. Grumbine, S. K. Mithani, A. Chatterjee, W. Koch, et al. (2007)
PNAS
104, 7540-7545
|Abstract »|Full Text »|PDF »