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Science 8 September 2006:
Vol. 313. no. 5792, p. 1360
DOI: 10.1126/science.313.5792.1360n
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This Week in Science

Hybrid sterility has been well studied for more than a century by many prominent scientists, including Darwin, but the molecular underpinnings have remained unidentified. Masly et al. (p. 1448) have identified a gene involved in sperm motility, JYAlpha, responsible for F2 hybrid sterility resulting from crosses of Drosophila melanogaster and D. simulans. During speciation gene translocation had placed the gene on two different chromosomes, leading to sterile F2 males lacking any copies of the gene. Thus, reproductive isolation can occur without sequence evolution.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)