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Science 25 August 2006:
Vol. 313. no. 5790, p. 1045
DOI: 10.1126/science.1127836
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Technical Comments

Comment on "Cell Type Regulates Selective Segregation of Mouse Chromosome 7 DNA Strands in Mitosis"

James E. Haber

Armakolas and Klar (Reports, 24 February 2006, p. 1146) suggested that segregation of mouse chromosome 7, after induction of a site-specific crossover between homologous chromosomes, is driven by a preferential inheritance of the old Watson and the old Crick DNA strands. However, this interpretation only considered half of the possible outcomes. The conjecture fails when all possible outcomes are examined.

Rosenstiel Center and Department of Biology, Brandeis University, Waltham, MA 02454–9110.

E-mail: haber{at}brandeis.edu

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Left-Right Dynein Motor Implicated in Selective Chromatid Segregation in Mouse Cells.
A. Armakolas and A. J. S. Klar (2007)
Science 315, 100-101
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