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Science 21 July 2006:
Vol. 313. no. 5785, pp. 308 - 309
DOI: 10.1126/science.1130482
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Perspectives

IMMUNOLOGY:
Considering Therapeutic Antibodies

Ellen S. Vitetta1* and Victor F. Ghetie1

Unexpected dangerous side effects of antibody-based therapies may be prevented with improved design of monoclonal antibodies and of clinical testing protocols.

1The authors are at the Cancer Immunobiology Center, University of Texas Southwestern Medical Center, 6000 Harry Hines Boulevard, Dallas, TX 75235-8576, USA.

*E-mail: ellen.vitetta{at}utsouthwestern.edu

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Science. ISSN 0036-8075 (print), 1095-9203 (online)