MEDICINE: Old Drug, New Hope for Marfan Syndrome

doi:10.1126/science.312.5770.36b

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Science 7 April 2006:
Vol. 312. no. 5770, pp. 36 - 37
DOI: 10.1126/science.312.5770.36b

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MEDICINE:
Old Drug, New Hope for Marfan Syndrome

John Travis

On page 117, researchers report that in a mouse model of Marfan syndrome, the blood pressure drug losartan prevents aortic aneurysms as well as lung problems sometimes seen in the condition. (Read more.)

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REPORTS Losartan, an AT1 Antagonist, Prevents Aortic Aneurysm in a Mouse Model of Marfan Syndrome: Jennifer P. Habashi, Daniel P. Judge, Tammy M. Holm, Ronald D. Cohn, Bart L. Loeys, Timothy K. Cooper, Loretha Myers, Erin C. Klein, Guosheng Liu, Carla Calvi, Megan Podowski, Enid R. Neptune, Marc K. Halushka, Djahida Bedja, Kathleen Gabrielson, Daniel B. Rifkin, Luca Carta, Francesco Ramirez, David L. Huso, and Harry C. Dietz (7 April 2006)
Science 312 (5770), 117. [DOI: 10.1126/science.1124287]
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Science. ISSN 0036-8075 (print), 1095-9203 (online)

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