Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 7 April 2006:
Vol. 312. no. 5770, p. 15
DOI: 10.1126/science.312.5770.15o
Prev | Table of Contents | Next

This Week in Science

Maintaining strict control over T cell numbers is essential for proper immune function, although many questions remain about how relative lymphocyte abundance is regulated. Hataye et al. (p. 114, published online 2 March) found that when a large number of identical T cells were present, the resulting population over time was unstable, with a considerably reduced half-life compared with smaller numbers of the same clonal population. In normal polyclonal T cell populations, such intraclonal jostling keeping numbers of particular clonal populations low would help to ensure that the greatest number of diverse clones can coexist at a given time.




ADVERTISEMENT
Click Me!

ADVERTISEMENT
Click Me!

To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)