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Science 24 March 2006:
Vol. 311. no. 5768, p. 1669
DOI: 10.1126/science.311.5768.1669g
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This Week in Science

What was the effect of developing the ability to use oxygen safely in metabolic reactions? Raymond and Segrè (p. 1764; see the Perspective by Falkowski) modeled how metabolic networks would have evolved from the Late Archean to Late Proterozoic periods of Earth's history. The complexity of networks that could use oxygen increased to levels far beyond those seen before the presence of oxygen. Comparisons between enzyme distributions and phylogenies suggest that adaptation to oxygen occurred after the major phylum-level divergences.




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