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VIROLOGY: Clues to the Virulence of H5N1 Viruses in Humans
Robert M. Krug
Why is H5N1 avian influenza so virulent? Genomic analysis of various isolates suggests that, in addition to two known surface proteins, a third previously unnoticed sequence in a small viral protein may contribute to virulence.
The author is at the Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX 78712, USA. E-mail: rkrug{at}mail.utexas.edu
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In Science Magazine
RESEARCH ARTICLES
John C. Obenauer, Jackie Denson, Perdeep K. Mehta, Xiaoping Su, Suraj Mukatira, David B. Finkelstein, Xiequn Xu, Jinhua Wang, Jing Ma, Yiping Fan, Karen M. Rakestraw, Robert G. Webster, Erich Hoffmann, Scott Krauss, Jie Zheng, Ziwei Zhang, and Clayton W. Naeve (17 March 2006) Science311 (5767), 1576.
[DOI: 10.1126/science.1121586] |Abstract »|Full Text »|PDF »|Supporting Online Material »
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Pathology, Molecular Biology, and Pathogenesis of Avian Influenza A (H5N1) Infection in Humans.
