Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 17 March 2006:
Vol. 311. no. 5767, p. 1517
DOI: 10.1126/science.311.5767.1517j
Prev | Table of Contents | Next

This Week in Science

Figure 1 Neural progenitors in the developing brain interact with neighboring cells through alphaE-catenin-containing adherens junctions. Lien et al. (p. 1609; see the Perspective by DiCicco-Bloom) found that conditional knock-out of the alphaE-catenin gene during embryonic brain development resulted in mice whose brains at birth contained twice as many cells as normal. It seems that the area of cell surface occupied by adherens junctions defines the density of cells and regulates cellular proliferation such that enough, but not too many, brain cells are produced.

CREDIT: LIEN ET AL.




To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)