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Science 3 March 2006:
Vol. 311. no. 5765, pp. 1251 - 1252
DOI: 10.1126/science.1125411
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Perspectives

STRUCTURAL BIOLOGY:
Architectural Options for a Fatty Acid Synthase

Stuart Smith

Multiple enzymes produce fatty acids in cells. These enzymes assemble into large complexes that are quite different in animals and fungi, but still carry out the same chemical synthesis.

The author is in the Children's Hospital Oakland Research Institute, Oakland, CA 94609, USA. E-mail: ssmith{at}chori.org

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
In Vivo Functional Analyses of the Type II Acyl Carrier Proteins of Fatty Acid Biosynthesis.
N. R. De Lay and J. E. Cronan (2007)
J. Biol. Chem. 282, 20319-20328
   Abstract »    Full Text »    PDF »
Salih Wakil's Elucidation of the Animal Fatty Acid Synthetase Complex Architecture.
N. Kresge, R. D. Simoni, and R. L. Hill (2006)
J. Biol. Chem. 281, e5
   Full Text »    PDF »


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