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Science 20 January 2006: Vol. 311. no. 5759, p. 299 DOI: 10.1126/science.311.5759.299l
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This Week in Science
The sequencing of ancient DNA is hoped to lend insight into evolutionary studies of a variety of species, including mammals. Poinar et al. (p. 392, published online 12 December 2005) used a roughly 28,000-year-old bone from a woolly mammoth that had been preserved in the Siberian permafrost to directly sequence ancient DNA without prior repair or amplification bias. A total of 137,000 reads (13 megabases) of mammoth DNA were generated, with only traces of human DNA contamination. Genomic comparisons were used to establish the rate of sequence divergence between extinct species and modern elephants. Examination of microbial and plant sequences isolated from the same source may also give clues about the mammoth's environment.
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Science. ISSN 0036-8075 (print), 1095-9203 (online)