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Science 4 November 2005:
Vol. 310. no. 5749, pp. 793 - 795
DOI: 10.1126/science.1120539
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Perspectives

STRUCTURAL BIOLOGY:
A Ribosomal Coup: E. coli at Last!

Peter B. Moore

In his Perspective, Moore discusses the atomic-resolution structure that has been obtained by Schuwirth et al. for the Escherichia coli ribosome, the enzyme responsible for protein synthesis in that organism. The vast body of biochemical and genetic data obtained for this particle over the past half century can now be interpreted structurally.

The author is in the Department of Chemistry, Yale University, New Haven, CT 06520-8107, USA. E-mail: peter.moore{at}yale.edu

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Science. ISSN 0036-8075 (print), 1095-9203 (online)