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GENOMICS: Thoughts on the Future of Great Ape Research
Edwin H. McConkey and Ajit Varki
In their Perspective, McConkey and Varki discuss the sequencing of the chimp genome, reported this week in the journal Nature. Although it is a notable accomplishment, it only marks the end of the beginning. The hard work of understanding how the genome generates the chimp phenome is still ahead of us, as is clarification of the precise differences between chimps and humans.
E. H. McConkey is in the Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309, USA. E-mail: mcconkey{at}colorado.edu A. Varki is in the Departments of Medicine and Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92039, USA. E-mail: a1varki{at}ucsd.edu
The editors suggest the following Related Resources on Science sites:
In Science Magazine
REPORTS
Philipp Khaitovich, Ines Hellmann, Wolfgang Enard, Katja Nowick, Marcus Leinweber, Henriette Franz, Gunter Weiss, Michael Lachmann, and Svante Pääbo (16 September 2005) Science309 (5742), 1850.
[DOI: 10.1126/science.1108296] |Abstract »|Full Text »|PDF »|Supporting Online Material »
Elizabeth Culotta (2 September 2005) Science309 (5740), 1468.
[DOI: 10.1126/science.309.5740.1468] |Summary »|Full Text »|PDF »
PERSPECTIVES
Marc D. Hauser (2 September 2005) Science309 (5740), 1498.
[DOI: 10.1126/science.1111421] |Summary »|Full Text »|PDF »
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Comparing the human and chimpanzee genomes: Searching for needles in a haystack.
