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Science 11 February 2005:
Vol. 307. no. 5711, pp. 836 - 839
DOI: 10.1126/science.307.5711.836
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News Focus

CELL BIOLOGY:
SUMO Wrestles Its Way to Prominence in the Cell

Jean Marx

The small protein SUMO is turning out to have as many roles in the cell as its better-known cousin, ubiquitin.

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Slx5 Promotes Transcriptional Silencing and Is Required for Robust Growth in the Absence of Sir2.
R. P. Darst, S. N. Garcia, M. R. Koch, and L. Pillus (2008)
Mol. Cell. Biol. 28, 1361-1372
   Abstract »    Full Text »    PDF »
The SUMO protease SENP5 is required to maintain mitochondrial morphology and function.
R. Zunino, A. Schauss, P. Rippstein, M. Andrade-Navarro, and H. M. McBride (2007)
J. Cell Sci. 120, 1178-1188
   Abstract »    Full Text »    PDF »
The ubiquitin-proteasome system in cardiac physiology and pathology.
S. R. Powell (2006)
Am J Physiol Heart Circ Physiol 291, H1-H19
   Abstract »    Full Text »    PDF »
The Ubiquitin-like Protein MNSFbeta Regulates ERK-MAPK Cascade.
M. Nakamura and S. Yamaguchi (2006)
J. Biol. Chem. 281, 16861-16869
   Abstract »    Full Text »    PDF »
Sumoylation Delimits KLF8 Transcriptional Activity Associated with the Cell Cycle Regulation.
H. Wei, X. Wang, B. Gan, A. M. Urvalek, Z. K. Melkoumian, J.-L. Guan, and J. Zhao (2006)
J. Biol. Chem. 281, 16664-16671
   Abstract »    Full Text »    PDF »
SUMO-1 Modification Alters ADAR1 Editing Activity.
J. M.P. Desterro, L. P. Keegan, E. Jaffray, R. T. Hay, M. A. O'Connell, and M. Carmo-Fonseca (2005)
Mol. Biol. Cell 16, 5115-5126
   Abstract »    Full Text »    PDF »


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