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Science 10 December 2004:
Vol. 306. no. 5703, pp. 1937 - 1940
DOI: 10.1126/science.1102210
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Reports

A Draft Sequence for the Genome of the Domesticated Silkworm (Bombyx mori)

Biology analysis group, Qingyou Xia,1*{dagger} Zeyang Zhou,1* Cheng Lu,1* Daojun Cheng,1 Fangyin Dai,1 Bin Li,1 Ping Zhao,1 Xingfu Zha,1 Tingcai Cheng,1 Chunli Chai,1 Guoqing Pan,1 Jinshan Xu,1 Chun Liu,1 Ying Lin,1 Jifeng Qian,1 Yong Hou,1 Zhengli Wu,1 Guanrong Li,1 Minhui Pan,1 Chunfeng Li,1 Yihong Shen,1 Xiqian Lan,1 Lianwei Yuan,1 Tian Li,1 Hanfu Xu,1 Guangwei Yang,1 Yongji Wan,1 Yong Zhu,1 Maode Yu,1 Weide Shen,1 Dayang Wu,1 Zhonghuai Xiang,1{dagger} Genome analysis group, Jun Yu,2,3*{dagger} Jun Wang,2,3* Ruiqiang Li,2* Jianping Shi,2 Heng Li,2 Guangyuan Li,2 Jianning Su,2 Xiaoling Wang,2 Guoqing Li,2 Zengjin Zhang,2 Qingfa Wu,2 Jun Li,2 Qingpeng Zhang,2 Ning Wei,2 Jianzhe Xu,2 Haibo Sun,2 Le Dong,2 Dongyuan Liu,2 Shengli Zhao,2 Xiaolan Zhao,2 Qingshun Meng,2 Fengdi Lan,2 Xiangang Huang,2 Yuanzhe Li,2 Lin Fang,2 Changfeng Li,2 Dawei Li,2 Yongqiao Sun,2 Zhenpeng Zhang,2 Zheng Yang,2 Yanqing Huang,2 Yan Xi,2 Qiuhui Qi,2 Dandan He,2 Haiyan Huang,2 Xiaowei Zhang,2 Zhiqiang Wang,2 Wenjie Li,2 Yuzhu Cao,2 Yingpu Yu,3 Hong Yu,3 Jinhong Li,3 Jiehua Ye,3 Huan Chen,3 Yan Zhou,3 Bin Liu,2 Jing Wang,2 Jia Ye,3 Hai Ji,2 Shengting Li,2 Peixiang Ni,2 Jianguo Zhang,2 Yong Zhang,2 Hongkun Zheng,2 Bingyu Mao,2 Wen Wang,2 Chen Ye,2 Songgang Li,2 Jian Wang,2,3 Gane Ka-Shu Wong,2,3,4{dagger} Huanming Yang2,3{dagger}

We report a draft sequence for the genome of the domesticated silkworm (Bombyx mori), covering 90.9% of all known silkworm genes. Our estimated gene count is 18,510, which exceeds the 13,379 genes reported for Drosophila melanogaster. Comparative analyses to fruitfly, mosquito, spider, and butterfly reveal both similarities and differences in gene content.

1 Southwest Agricultural University, Chongqing Beibei, 400716, China.
2 Beijing Institute of Genomics of Chinese Academy of Sciences, Beijing Genomics Institute, Beijing Proteomics Institute, Beijing 101300, China.
3 James D. Watson Institute of Genome Sciences of Zhejiang University, Hangzhou Genomics Institute, Key Laboratory of Genomic Bioinformatics of Zhejiang Province, Hangzhou 310008, China.
4 University of Washington Genome Center, Department of Medicine, University of Washington, Seattle, WA 98195, USA.



* These authors contributed equally to this work.

{dagger} To whom correspondence should be addressed. E-mail: xiaqy{at}swau.cq.cn (Q.X.), xzh{at}swau.cq.cn (Z.X.), junyu{at}genomics.org.cn (J.Y.), gksw{at}genomics.org.cn (G.K-S.W.), yanghm{at}genomics.org.cn (H.Y.)

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