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Science 23 July 2004:
Vol. 305. no. 5683, pp. 482 - 483
DOI: 10.1126/science.1101133
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Perspectives

NEUROSCIENCE:
Epileptic Neurons Go Wireless

Kevin Staley

Neuroscientists have long been puzzled by the fact that prolonged epileptic seizures facilitate future seizures. In his Perspective, Staley discusses a recent study in a rat model of temporal lobe epilepsy (Bernard et al.), which shows that a contributory factor to this facilitation is the loss of inhibitory K+ ion currents called A currents.

The author is in the Department of Neurology and Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80262, USA. E-mail: kevin.staley{at}uchsc.edu

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Science. ISSN 0036-8075 (print), 1095-9203 (online)