Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 2 July 2004:
Vol. 305. no. 5680, pp. 48 - 49
DOI: 10.1126/science.1100153
Prev | Table of Contents | Next

Perspectives

CELL BIOLOGY:
The Golgi Goes Fission

Aipo Diao and Martin Lowe

Like other cellular organelles, the Golgi apparatus has to be divided equally between the two daughter cells that result from mitosis. The first step in this process is fragmentation of the Golgi, followed by fission of the Golgi membranes during early mitosis. As Diao and Lowe discuss in their Perspective, new findings (Hidalgo Carcedo et al.) show that Golgi membrane fission induced by the CtBP3/BARS protein is required before cells can enter mitosis.

The authors are at the School of Biological Sciences, University of Manchester, Oxford Road, Manchester M13 9PT, UK. E-mail: martin.lowe{at}man.ac.uk

Read the Full Text


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Monocrotaline pyrrole-induced endothelial cell megalocytosis involves a Golgi blockade mechanism.
M. Shah, K. Patel, and P. B. Sehgal (2005)
Am J Physiol Cell Physiol 288, C850-C862
   Abstract »    Full Text »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)