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Science 11 June 2004:
Vol. 304. no. 5677, p. 1577
DOI: 10.1126/science.304.5677.1577
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News of the Week

IMMUNOLOGY:
Unexpectedly, Ancient Molecule Tied to Asthma

Jennifer Couzin

A surprise discovery in mice, reported on page 1678, has linked a mysterious, largely unexplored class of molecules to asthma and may bolster the theory that the respiratory disease is a misplaced reaction to parasites.

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
A Chitinase-like Protein in the Lung and Circulation of Patients with Severe Asthma.
G. L. Chupp, C. G. Lee, N. Jarjour, Y. M. Shim, C. T. Holm, S. He, J. D. Dziura, J. Reed, A. J. Coyle, P. Kiener, et al. (2007)
N. Engl. J. Med. 357, 2016-2027
   Abstract »    Full Text »    PDF »
Marked Differences in Tissue-specific Expression of Chitinases in Mouse and Man.
R. G. Boot, A. P. Bussink, M. Verhoek, P. A.J. de Boer, A. F.M. Moorman, and J. M.F.G. Aerts (2005)
J. Histochem. Cytochem. 53, 1283-1292
   Abstract »    Full Text »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)