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Science 25 July 2003:
Vol. 301. no. 5632, pp. 452 - 454
DOI: 10.1126/science.301.5632.452
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News Focus

ANGIOGENESIS:
A Boost for Tumor Starvation

Jean Marx

Despite some setbacks, researchers developing antiangiogenesis treatments for cancer have persevered. Now the strategy is racking up new successes and earning credit even for conventional treatments.

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Tumor Recovery by Angiogenic Switch from Sprouting to Intussusceptive Angiogenesis after Treatment with PTK787/ZK222584 or Ionizing Radiation.
R. Hlushchuk, O. Riesterer, O. Baum, J. Wood, G. Gruber, M. Pruschy, and V. Djonov (2008)
Am. J. Pathol. 173, 1173-1185
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Introduction.
P. A. Bunn Jr. and N. Thatcher (2008)
Oncologist 13, 1-4
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Structure-Function Studies of Two Synthetic Anti-vascular Endothelial Growth Factor Fabs and Comparison with the AvastinTM Fab.
G. Fuh, P. Wu, W.-C. Liang, M. Ultsch, C. V. Lee, B. Moffat, and C. Wiesmann (2006)
J. Biol. Chem. 281, 6625-6631
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Depletion of Securin Increases Arsenite-Induced Chromosome Instability and Apoptosis via a p53-Independent Pathway.
J.-I Chao, S.-H. Hsu, and T.-C. Tsou (2006)
Toxicol. Sci. 90, 73-86
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Improved Therapeutic Effectiveness by Combining Recombinant CXC Chemokine Ligand 10 with Cisplatin in Solid Tumors.
G. Li, L. Tian, J.-m. Hou, Z.-y. Ding, Q.-m. He, P. Feng, Y.-j. Wen, F. Xiao, B. Yao, R. Zhang, et al. (2005)
Clin. Cancer Res. 11, 4217-4224
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Imaging Angiogenesis: Applications and Potential for Drug Development.
J. C. Miller, H. H. Pien, D. Sahani, A. G. Sorensen, and J. H. Thrall (2005)
J Natl Cancer Inst 97, 172-187
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A key angiogenic role of monocyte chemoattractant protein-1 in hemangioendothelioma proliferation.
G. M. Gordillo, D. Onat, M. Stockinger, S. Roy, M. Atalay, F. M. Beck, and C. K. Sen (2004)
Am J Physiol Cell Physiol 287, C866-C873
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Dynamic Magnetic Resonance Perfusion Imaging of Brain Tumors.
D. J. Covarrubias, B. R. Rosen, and M. H. Lev (2004)
Oncologist 9, 528-537
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Intravenous liposomal delivery of the snake venom disintegrin contortrostatin limits breast cancer progression.
S. Swenson, F. Costa, R. Minea, R. P. Sherwin, W. Ernst, G. Fujii, D. Yang, and F. S. Markland Jr. (2004)
Mol. Cancer Ther. 3, 499-511
   Abstract »    Full Text »    PDF »


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