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Science 27 June 2003:
Vol. 300. no. 5628, pp. 2040 - 2041
DOI: 10.1126/science.1084938
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Perspectives

CELL BIOLOGY:
Microtubule Asymmetry

Gregg G. Gundersen and Anthony Bretscher

How does the cell arrange for the asymmetric distribution of microtubules during spindle formation and cell division? In their Perspective, Gundersen and Bretscher discuss new work published elsewhere that shows how certain proteins become loaded onto microtubules and cooperate with actin cables to guide the microtubule tips to a new location.

G. G. Gundersen is in the Department of Anatomy and Cell Biology and Department of Pathology, Columbia University, New York, NY 10032, USA. E-mail: ggg1{at}columbia.edu A. Bretscher is in the Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA. E-mail: apb5{at}cornell.edu

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
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ADF/cofilin family proteins control formation of oriented actin-filament bundles in the cell body to trigger fibroblast polarization.
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The Conserved Spc7 Protein Is Required for Spindle Integrity and Links Kinetochore Complexes in Fission Yeast.
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The Fission Yeast Kinetochore Component Spc7 Associates with the EB1 Family Member Mal3 and Is Required for Kinetochore-Spindle Association.
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The Kip3-Like Kinesin KipB Moves along Microtubules and Determines Spindle Position during Synchronized Mitoses in Aspergillus nidulans Hyphae.
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