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BIOMEDICINE: A View from the Top--Prion Diseases from 10,000 Feet
Suzette A. Priola, Bruce Chesebro, Byron Caughey
The transmissible spongiform encephalopathies or prion diseases include scrapie in sheep, mad cow disease, and variant Creutzfeld-Jakob disease in humans. The agent of all of these diseases is thought to be a self-replicating protein or prion. In a report of a recent meeting on prion diseases, Priola, Chesebro, and Caughey discuss the latest developments in this often contentious field of research.
The authors are in the Laboratory of Persistent Viral Diseases, National Institute of Allergy and Infectious Diseases, Rocky Mountain Laboratories, Hamilton, MT 59840, USA. E-mail: spriola{at}nih.gov
The editors suggest the following Related Resources on Science sites:
In Science Magazine
LETTERS
Andrea C. LeBlanc, Xavier Roucou;, Suzette A. Priola, Byron Caughey, and Bruce Chesebro (11 July 2003) Science301 (5630), 168.
[DOI: 10.1126/science.301.5630.168] |Full Text »|PDF »
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
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Calpain and Other Cytosolic Proteases Can Contribute to the Degradation of Retro-translocated Prion Protein in the Cytosol.
