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Science 9 May 2003:
Vol. 300. no. 5621, pp. 913 - 916
DOI: 10.1126/science.1082940
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Perspectives

Also see the archival list of Science's Compass: Enhanced Perspectives

STEM CELLS:
Enhanced: Setting Standards for Human Embryonic Stem Cells

Ali H. Brivanlou, Fred H. Gage, Rudolf Jaenisch, Thomas Jessell, Douglas Melton, Janet Rossant

Human embryonic stem cells (HESCs) have great potential in regenerative medicine and provide a window on early human embryonic development. In their Perspective, Brivanlou and colleagues review our current understanding of the cellular, molecular, and embryological properties of HESCs and suggest how standardized measures could be used to facilitate comparison across different human embryonic cell lines.

A. H. Brivanlou is at the Rockefeller University, New York, NY 10021, USA. E-mail: brvnlou{at}rockefeller.edu F. H. Gage is at the Salk Institute for Biological Sciences, San Diego, CA 92037, USA. R. Jaenisch is at the Whitehead Institute, Cambridge, MA 02142-1479, USA. T. Jessell is a Howard Hughes Medical Institute investigator at Columbia University, New York, NY 10032, USA. D. Melton is at Harvard University, Cambridge, MA 02138, USA. J. Rossant is at Mount Sinai Hospital, Toronto, Ontario M5G 1X5, Canada.

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