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Science 7 March 2003:
Vol. 299. no. 5612, pp. 1502 - 1505
DOI: 10.1126/science.299.5612.1502
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News Focus

INFECTIOUS DISEASE:
Chasing the Fickle Swine Flu

Bernice Wuethrich

After years of stability, the North American swine flu virus has jumped onto an evolutionary fast track, churning out variants every year. Changes in animal husbandry, including increased vaccination, may be spurring this evolutionary surge. And if one of this slew of swine strains gains the ability to spread among people--as has apparently happened at least twice before--the consequences could be deadly.

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
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Co-infection Weakens Selection Against Epistatic Mutations in RNA Viruses.
R. Froissart, C. O. Wilke, R. Montville, S. K. Remold, L. Chao, and P. E. Turner (2004)
Genetics 168, 9-19
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Science. ISSN 0036-8075 (print), 1095-9203 (online)