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Science 28 February 2003:
Vol. 299. no. 5611, pp. 1290 - 1291
DOI: 10.1126/science.299.5611.1290
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News of the Week

PUBLIC HEALTH:
AIDS Vaccine Trial Produces Disappointment and Confusion

Jon Cohen

VaxGen says that when the data from its first-ever real-world test of an AIDS vaccine were broken down into racial groups, the vaccine appeared to have worked in black, Asian, and mixed-race participants. But hours after VaxGen made the data public, AIDS researchers began pasting asterisks and red flags all over the results.

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Evaluating the Immunogenicity of a Disulfide-Stabilized, Cleaved, Trimeric Form of the Envelope Glycoprotein Complex of Human Immunodeficiency Virus Type 1.
S. Beddows, N. Schulke, M. Kirschner, K. Barnes, M. Franti, E. Michael, T. Ketas, R. W. Sanders, P. J. Maddon, W. C. Olson, et al. (2005)
J. Virol. 79, 8812-8827
   Abstract »    Full Text »    PDF »
The V1/V2 Domain of gp120 Is a Global Regulator of the Sensitivity of Primary Human Immunodeficiency Virus Type 1 Isolates to Neutralization by Antibodies Commonly Induced upon Infection.
A. Pinter, W. J. Honnen, Y. He, M. K. Gorny, S. Zolla-Pazner, and S. C. Kayman (2004)
J. Virol. 78, 5205-5215
   Abstract »    Full Text »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)