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Science 20 December 2002:
Vol. 298. no. 5602, pp. 2296 - 2297
DOI: 10.1126/science.298.5602.2296
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BREAKTHROUGH OF THE YEAR:
Small RNAs Make Big Splash

Jennifer Couzin

Just when scientists thought they had deciphered the roles played by the cell's leading actors, a familiar performer has turned up in a stunning variety of guises. RNA, long upstaged by its more glamorous sibling, DNA, is turning out to have star qualities of its own. Science hails these electrifying discoveries, which are prompting biologists to overhaul their vision of the cell and its evolution, as 2002's Breakthrough of the Year. The online version of the Breakthrough of the Year section contains references and links not found in the print edition (see www.sciencemag.org/content/vol298/issue5602/#special).

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Science. ISSN 0036-8075 (print), 1095-9203 (online)