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Science 29 November 2002:
Vol. 298. no. 5599, p. 1726
DOI: 10.1126/science.1079874
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Viewpoints

HISTORICAL ESSAY:
Discovering the Cause of AIDS

Stanley B. Prusiner

It is almost 20 years since HIV was first isolated and identified as the cause of AIDS. In this introductory Viewpoint, Prusiner details the early days of the AIDS epidemic and the huge task of trying to identify its cause. He introduces Viewpoints by Gallo and Montagnier, who describe the different yet complementary paths that each took to discover that HIV, a new human retrovirus, is the cause of AIDS.

The author is at the Institute for Neurodegenerative Diseases, Department of Neurology and Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94143, USA.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)