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Science 22 November 2002:
Vol. 298. no. 5598, pp. 1610 - 1613
DOI: 10.1126/science.1073906
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Reports

Genetic Evidence for an East Asian Origin of Domestic Dogs

Peter Savolainen,1* Ya-ping Zhang,2 Jing Luo,2dagger Joakim Lundeberg,1 Thomas Leitner3

The origin of the domestic dog from wolves has been established, but the number of founding events, as well as where and when these occurred, is not known. To address these questions, we examined the mitochondrial DNA (mtDNA) sequence variation among 654 domestic dogs representing all major dog populations worldwide. Although our data indicate several maternal origins from wolf, >95% of all sequences belonged to three phylogenetic groups universally represented at similar frequencies, suggesting a common origin from a single gene pool for all dog populations. A larger genetic variation in East Asia than in other regions and the pattern of phylogeographic variation suggest an East Asian origin for the domestic dog, ~15,000 years ago.

1 Department of Biotechnology, Royal Institute of Technology (KTH), 10691 Stockholm, Sweden.
2 Yunnan Laboratory of Molecular Biology of Domestic Animals, and Laboratory of Molecular Evolution and Genome Diversity, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China.
3 Department of Virology, Swedish Institute for Infectious Disease Control, 17182 Solna, Sweden.
*   To whom correspondence should be addressed. E-mail: savo{at}biotech.kth.se

dagger    Present address: Department of Biology, University of Konstanz, 78457 Konstanz, Germany.

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