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Science 15 November 2002:
Vol. 298. no. 5597, p. 1319
DOI: 10.1126/science.298.5597.1319
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News of the Week

IMMUNOLOGY:
Antibodies Kill by Producing Ozone

Jean Marx

In work published online today by Science, researchers report evidence that antibodies can catalyze the production of highly active forms of oxygen, likely including ozone. This can not only kill bacterial pathogens directly but might also promote inflammatory and other immune responses. The work puts antibodies in a whole new light, because they weren't previously supposed to have such direct effects.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)