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Science 18 October 2002:
Vol. 298. no. 5593, p. 491
DOI: 10.1126/science.298.5593.491m
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This Week in Science

Are there genes that characterize various sets of stem cells? Ivanova et al. (p. 601) and Ramalho-Santos et al. (p. 597) used transcriptional profiling of mammalian embryonic and adult stem cells to identify genes that are common among hematopoietic stem cells, embryonic stem cells, and neural stem cells. These subsets of genes may provide stem cells with the ability to self-renew, to generate differentiated cells, or to do both, and hence represent, according to the authors, "stemness" or a "stem cell molecular signature."




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Science. ISSN 0036-8075 (print), 1095-9203 (online)