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Science 16 August 2002:
Vol. 297. no. 5584, pp. 1135 - 1136
DOI: 10.1126/science.1074492
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Perspectives

DEVELOPMENT:
Doublesex in the Middle

Kenneth C. Burtis

What are the molecular mechanisms that determine the acquisition of male and female sexual characteristics? In a Perspective, Ken Burtis reviews a series of recent papers published elsewhere that elucidate the part played by the transcription factor, doublesex, in determining sexual dimorphism in the fruit fly.

The author is in the Department of Molecular and Cellular Biology, University of California, Davis, CA 95616, USA. E-mail: kcburtis{at}ucdavis.edu

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Regulation of Sexual Dimorphism: Mutational and Chemogenetic Analysis of the Doublesex DM Domain.
W. Zhang, B. Li, R. Singh, U. Narendra, L. Zhu, and M. A. Weiss (2006)
Mol. Cell. Biol. 26, 535-547
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