Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.
Also see the archival list of Science's Compass: Enhanced Perspectives
PARASITOLOGY: Enhanced: Malaria--from Infants to Genomics to Vaccines
Carole A. Long and Stephen L. Hoffman
Tropical protozoan parasites are the scourge of the developing world, causing devastating diseases, such as malaria, Chagas' disease, and leishmaniasis. These diseases not only are a huge cause of human misery but also are holding back the economic progress of many developing countries. A pair of Perspectives--by Hol and Gelb, and by Long and Hoffman--report the proceedings of two recent Keystone meetings that examined progress in developing new drugs and vaccines to combat these terrible diseases.
C. A. Long is at the Malaria Vaccine Development Unit, National Institutes of Health, Rockville, MD 20852, USA. E-mail: clong{at}niaid.nih.gov S. L. Hoffman is at Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA.
PfSPATR, a Plasmodium falciparum Protein Containing an Altered Thrombospondin Type I Repeat Domain Is Expressed at Several Stages of the Parasite Life Cycle and Is the Target of Inhibitory Antibodies.
R. Chattopadhyay, D. Rathore, H. Fujioka, S. Kumar, P. de la Vega, D. Haynes, K. Moch, D. Fryauff, R. Wang, D. J. Carucci, et al. (2003)
J. Biol. Chem.
278, 25977-25981
|Abstract »|Full Text »|PDF »
