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Science 12 July 2002:
Vol. 297. no. 5579, pp. 175 - 177
DOI: 10.1126/science.297.5579.175a
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News of the Week

EMBRYONIC STEM CELLS:
Stem Cells Not So Stealthy After All

Gretchen Vogel

As human embryonic stem (ES) cells differentiate, they express increasing levels of the telltale tags the body uses to distinguish between native and foreign cells. The findings, published online this week by the Proceedings of the National Academy of Sciences, confirm that a patient's immune system would be likely to reject transplanted tissues derived from ES cells. Scientists will therefore have to find ways to reconcile the body's defense system with the transplanted cells.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)