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Science 5 July 2002:
Vol. 297. no. 5578, pp. 62 - 63
DOI: 10.1126/science.1073843
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Perspectives

NANOTECHNOLOGY:
Tools for the Biomolecular Engineer

Christof M. Niemeyer

As traditional "top-down" approaches to device fabrication are reaching their limits, "bottom-up" approaches based on the assembly of individual molecules are receiving increasing attention. Biomolecules such as DNA are particularly promising because of their specific recognition capabilities. In his Perspective, Niemeyer highlights the molecular lithography approach developed by Keren et al. Combined with protein bioengineering, molecular lithography provides a new, powerful tool for using DNA in future nanometer-scale devices.

The author is at the Chemistry Department, University of Dortmund, 44227 Dortmund, Germany. E-mail: cmn{at}chemie.uni-dortmund.de

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Science. ISSN 0036-8075 (print), 1095-9203 (online)