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Science 8 February 2002:
Vol. 295. no. 5557, pp. 984 - 985
DOI: 10.1126/science.1069485
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Perspectives

TRANSCRIPTION:
Mediator Meets Morpheus

Michael Meisterernst

Deciphering how the numerous coactivators of transcription work is a formidable task. In his Perspective, Meisterernst discusses the implications of new findings (Taatjes et al.) that describe the structures of the ARC-L and CRSP coactivator complexes and their interactions with transcriptional activators.

The author is in the Gene Expression Department, National Research Center for Environment and Health-GSF Institute of Molecular Immunology, Marchionini-Strasse 25, D-81377 Munich, Germany.

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
TATA-binding Protein-free TAF-containing Complex (TFTC) and p300 Are Both Required for Efficient Transcriptional Activation.
S. Hardy, M. Brand, G. Mittler, J. Yanagisawa, S. Kato, M. Meisterernst, and L. Tora (2002)
J. Biol. Chem. 277, 32875-32882
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