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Science 5 October 2001:
Vol. 294. no. 5540, p. 33
DOI: 10.1126/science.294.5540.33a
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News of the Week

GENOME RESEARCH:
Possible New Heart Disease Risk Factor

Caroline Seydel

After embarking on a basic study of gene regulation, a research team has instead uncovered a new gene that may be an important risk factor in cardiovascular diseases. The new gene, reported on page 169, encodes a previously unknown member of the apolipoprotein family of proteins, which influence blood lipid levels. The researchers have also shown that mutations in the gene lead to increased blood triglyceride levels in both mice and humans.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)