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Science 27 April 2001:
Vol. 292. no. 5517, pp. 615 - 617
DOI: 10.1126/science.292.5517.615b
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News of the Week

DEVELOPMENTAL BIOLOGY:
Stem Cells Are Coaxed to Produce Insulin

Gretchen Vogel

In a paper published online today by Science (www.sciencexpress.org), researchers describe a five-step culturing technique that can turn mouse embryonic stem cells into cell clusters that resemble the insulin-producing islets of the pancreas. The cells produce small amounts of insulin and seem to behave similarly to normal pancreas cells. Important caveats remain, however.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)