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Science 6 April 2001:
Vol. 292. no. 5514, pp. 44 - 45
DOI: 10.1126/science.292.5514.44
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COMPARATIVE GENOMICS:
Gene Expression Differs in Human and Chimp Brains

Dennis Normile

TOKYO--Genetic variation may explain why humans differ from their primate cousins, but not in the way one might expect. Although the human genome differs only slightly--an estimated 1% to 2%--from those of the great apes, there are significant differences in how genes are expressed and regulated. New research reported at a meeting here last month suggests that those differences are most marked in the brain, a finding that offers possible clues to how humans developed their prodigious mental capacity.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)