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Modulation of Oscillatory Neuronal Synchronization by Selective Visual Attention
Pascal Fries,1*John H. Reynolds,12Alan E. Rorie,1Robert Desimone1
In crowded visual scenes, attention is needed to select
relevant stimuli. To study the underlying mechanisms, we recordedneurons in cortical area V4 while macaque monkeys attended tobehaviorally relevant stimuli and ignored distracters. Neuronsactivated by the attended stimulus showed increased gamma-frequency(35 to 90 hertz) synchronization but reduced low-frequency (<17hertz)
synchronization compared with neurons at nearby V4 sitesactivated by
distracters. Because postsynaptic integration timesare short, these
localized changes in synchronization may serveto amplify behaviorally
relevant signals in the cortex.
1 Laboratory of Neuropsychology, National
Institute of Mental Health, National Institutes of Health, Building 49, Room 1B80, 9000 Rockville Pike, Bethesda, MD 20892-4415, USA.
2 Systems Neurobiology Laboratory, The Salk
Institute for Biological Studies, 10010 North Torrey Pines Road, La
Jolla, CA 92037-1099, USA.
*
To whom correspondence should be addressed. E-mail:
fries{at}ln.nimh.nih.gov
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PERSPECTIVES
Michael P. Stryker (23 February 2001) Science291 (5508), 1506.
[DOI: 10.1126/science.291.5508.1506] |Summary »|Full Text »
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